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Late-breaking Phase III IgAN data for Vanrafia ALIGN and Fabhalta APPLAUSE-IgAN studies to be presented
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124-week Phase I/II zigakibart data evaluating treatment efficacy and safety in IgAN will be featured
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New insights into disease characteristics in IgAN and C3G inform future research and treatment approaches
Basel, May 26, 2026 – Novartis will present data from 15 abstracts from its kidney portfolio at this year’s European Renal Association (ERA) Congress in Glasgow, June 3-6. The presentations reinforce our ambition to advance scientific understanding across progressive immune-mediated kidney diseases and support the evolution of kidney care.
Presentations include late-breaking Phase III results for Vanrafia® (atrasentan) and Fabhalta® (iptacopan), along with extended follow-up data from the investigational anti-APRIL therapy zigakibart in IgA nephropathy (IgAN). Separate analyses will also explore disease characteristics in IgAN and C3 glomerulopathy (C3G).
“At ERA this year, Novartis will present important late-stage and long-term data in IgAN, alongside broader insights across our kidney disease portfolio,” said Ruchira Glaser, MD, MS, Global Head, Cardiovascular, Renal and Metabolic Development, Novartis. “Together, these findings reflect our continued innovation and a science-driven approach to generating evidence that informs the future of kidney care.”
Key abstracts accepted by ERA include:
Novartis’ commitment to kidney diseases
Building on a legacy of more than 40 years that began in transplant, Novartis is on a mission to empower breakthroughs and transform care in kidney health, starting with kidney conditions that have significant unmet need.
Historically, these conditions have had considerably less funding and research, leading to a treatment landscape largely focused on reactive or end-stage disease management, often with significant physical, emotional, and financial burdens. Our portfolio targets the underlying causes of disease, with an aim to protect kidney health and delay or prevent dialysis and/or transplantation. Our goal is to help patients get back to living life on their terms - whether at work, in school, or with loved ones, and by partnering with patients, advocates, clinicians and policymakers, we aim to raise awareness, accelerate diagnosis, and get patients the right care, sooner.
About Novartis
Novartis is an innovative medicines company. Every day, we work to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 300 million people worldwide.